Optimal sampling for pedigree analysis: tracing a single gene
- 1 December 1982
- journal article
- Published by Cambridge University Press (CUP) in Advances in Applied Probability
- Vol. 14 (4) , 752-762
- https://doi.org/10.2307/1427022
Abstract
In fitting genetic models on the basis of observations on an interrelated structure, sequential procedures can enhance efficiency. In this paper we consider the case of a rare gene segregating in a single large pedigree. The sampling rule is dictated by the effect of observations on the genotypic probability distribution of unobserved relatives; this effect is investigated.Keywords
This publication has 1 reference indexed in Scilit:
- Probability functions on complex pedigreesAdvances in Applied Probability, 1978