Probing the Probes: Fitness Factors For Small Molecule Tools

This publication has 143 references indexed in Scilit:

• Rationalizing the chemical space of protein–protein interaction inhibitors
  Drug Discovery Today, 2010
• Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
  Published by Elsevier ,2010
• The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors
  Nature Chemical Biology, 2010
• HTS and hit finding in academia – from chemical genomics to drug discovery
  Drug Discovery Today, 2009
• Predicting new molecular targets for known drugs
  Nature, 2009
• Measuring and interpreting the selectivity of protein kinase inhibitors
  Journal of Chemical Biology, 2009
• Lead-like, drug-like or “Pub-like”: how different are they?
  Journal of Computer-Aided Molecular Design, 2007
• A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling
  Cell, 2006
• BRAF mutation predicts sensitivity to MEK inhibition
  Nature, 2005
• Initial sequencing and analysis of the human genome
  Nature, 2001