PREPARATION AND PROPERTIES OF CRYSTALLINE CANDIDIN

1 September 1956

journal article
Published by Canadian Science Publishing in Canadian Journal of Chemistry

Vol. 34 (9) , 1163-1167
https://doi.org/10.1139/v56-152

Abstract

Candidin, the antifungal antibiotic produced by Streptomycesviridoflavus, has been isolated in crystalline form. Analyses and equivalent weight values best fit a molecular formula C₄₆H₇₅NO₁₇. The substance is amphoteric and probably contains one carboxyl and one amino group. Infrared spectral evidence also indicates a polyhydroxylated structure, and the absorption in the visible region shows the presence of a conjugated heptaene chromophore. An additional conjugated diene elsewhere in the molecule is suggested by hydrogenation values and the absorption maximum at 228 mμ.

Keywords

This publication has 2 references indexed in Scilit:

AN AGAR DIFFUSION ASSAY METHOD FOR THE ANTIFUNGAL POLYENE, CANDIDIN
Canadian Journal of Microbiology, 1956
Candicidin, A New Antifungal Antibiotic
Mycologia, 1953