Bacillus Calmette-Guerin Immunotherapy of Infiltrating Bladder Cancer

Abstract
Oral administration of BCG was used to treat 10 patients with muscle invasive transitional cell carcinoma of the bladder. The treatment induced tumor regression in 7 patients (70%), including 1 who died without evidence of recurrent tumor. Skin test reactivity was correlated with response to treatment. Only 1 patient had marked skin test reactivity at the time of tumor recurrence. Patients with invasive bladder cancer may derive benefit from immunotherapy.