Extremely mild reagent for Boc deprotection applicable to the synthesis of peptides with thioamide linkages

1 January 1996

journal article
research article
Published by Royal Society of Chemistry (RSC) in Chemical Communications

No. 22,p. 2509-2510
https://doi.org/10.1039/cc9960002509

Abstract

SnCl₄ in organic solvents acts as an extremely mild reagent for Boc deprotection even in the presence of the acid-labile thioamide moiety with excellent yields.

Keywords

EXTREMELY
MILD REAGENT
BOC
SNCL4
LINKAGES
LABILE
MOIETY
DEPROTECTION APPLICABLE

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