Endocrine-Paracrine Cells in Prostatic Carcinoma and Clinical Course of the Disease

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Abstract
The occurrence of endocrine-paracrine (argyrophil and argentaffin) cells in normal and hyperplastic human epithelia has long been recognized. 40 consecutive prostatic carcinomas were studied histochemically and ultrastructurally. The authors consider only clinically evaluable cases and discuss the clinical significance of the presence of endocrine-paracrine cells on the basis of their personal experience.