Resistance to imipenem in Pseudomonas aeruginosa
- 1 December 1995
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 36 (6) , 1037-1041
- https://doi.org/10.1093/jac/36.6.1037
Abstract
There was a slow increase in imipenem resistance in Pseudomonas aeruginosa at St. Thomas' Hospital in the 1990s, reaching 3% in 1994. Of the 94 imipenem-resistant strains, 69% were susceptible to all the other agents tested; 15% were also resistant to one other antibiotic, 5.3% to two, 6.4% to three, 4.3% to four or more compounds. 16% of strains were resistant to at least one other β-lactam in addition to imipenem. Resistance to other antibiotics was more common among the strains for which imipenem MICs were 4mg/L than among either imipenem-susceptible or imipenem-resistant (MICs ≥8 mg/L) strains.Keywords
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