Fatal Uremia Due to Uric Acid Crystals in a Case of Lymphosarcoma

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Abstract
ONE OF THE RARE and partially avoidable complications of the lymphoma group of neoplasms is uremia as the result of precipitation of uric acid in the urinary tract. This has received considerable attention in the general medical and hematological literature, but is perhaps not sufficiently well known to the radiologist. A recent example at the Philadelphia Veterans Administration Hospital focused our attention upon it. C. O'H. , a 24-year-old white male, was admitted on May 16, 1956, with a one-month history of hematemesis, anorexia, and weight loss totaling ,50 pounds. An epigastric mass had been apparent for two days, and this was the sole significant physical finding. The hemoglobin was 12.0 gm. and the white blood cell count was normal. Urinalysis showed an alkaline urine containing 2+ albumin and 50 to 60 rea blood cells per high-power field. An initial blood urea nitrogen of 55 mg. per cent rose in two days to 80 mg. per cent, in spite of fluid therapy. An upper gastrointestinal series showed a comp...

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