Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer
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Open Access
- 28 April 2009
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 100 (10) , 1603-1607
- https://doi.org/10.1038/sj.bjc.6605058
Abstract
Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.Keywords
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