αααanti-4.2 Haplotype and heterozygous β° thalassemia in a Sicilian family
- 1 August 1985
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 70 (4) , 318-320
- https://doi.org/10.1007/bf00295368
Abstract
The presence of the αααanti-4.2 haplotype and heterozygous β° thalassemia in a Sicilian family is described. These findings confirm the presence in Italy of a leftward deletion (−α4.2) and indicate that this may not be rare. Furthermore, although the β thalassemia determinant in this family has a severe expression, the interaction with the triplicated α gene does not necessarily express itself as thalassemia intermedia.Keywords
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