Human Immunoglobulin A: Production of an Fc Fragment by an Enteric Microbial Proteolytic Enzyme
Open Access
- 1 October 1973
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 111 (4) , 1274-1276
- https://doi.org/10.4049/jimmunol.111.4.1274
Abstract
Summary: An Fc fragment has been prepared in good yield by proteolytic cleavage of human secretory and serum myeloma IgA with an enzyme recovered from the human gastrointestinal tract. The naturally occurring enzyme is of microbial origin and its activity is metal dependent.Keywords
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