Hb F-Tokyo or α2GΓ234(B16) Val→Ile, A Silent Γ Chain Variant Detected by Reverse Phase high Performance Liquid Chromatography
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 9 (1) , 25-32
- https://doi.org/10.3109/03630268508996979
Abstract
Hb F-Tokyo with a Valine→Isoleucine replacement at position γ34(B16) is a Gγ chain variant which was discovered by reverse phase chromatography as this method permitted the nearly complete separation of the three types of γ chain. The chemical characterization was greatly facilitated by the use of a larger, preparative, HPLC column which allowed the isolation of sufficient quantities of the different γ chains.This publication has 5 references indexed in Scilit:
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