Dose Fractionation Effects in Low Dose Rate Irradiation of Jejunal Crypt Stem Cells

Abstract
Jejunal crypt survival after fractionated total body irradiation of C3H mice given at dose rates of 1.2 or 0.08 Gy [gray]/min was studied. The fractionation effect was more pronounced at the high dose rate than at the low dose rate. Analysis of the data according to the linear-quadratic survival curve model yielded an .alpha./.beta. value at 1.2 Gy/min of 13.3 Gy and 0.08 Gy/min of 96 Gy.
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