Olanzapine treatment of anorexia nervosa: A retrospective study

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Abstract
Background: Recent reports raise the possibility that olanzapine, which commonly causes weight gain in non–eating‐disordered subjects, assisted weight gain and mood during refeeding in anorexia nervosa (AN) patients.Methods: Eighteen AN subjects who engaged in open treatment with olanzapine were retrospectively questioned about their response.Results: Subjects reported a significant reduction in anxiety, difficulty eating, and core eating disorder symptoms after taking olanzapine.Discussion: These data lend support to the possibility that olanzapine may be useful in AN patients.Conclusion: A controlled trial is necessary to prove that olanzapine is efficacious. © 2003 by Wiley Periodicals, Inc. Int J Eat Disord 33: 234–237, 2003.

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