Sodium cromoglycate in histamine and methacholine reactivity in asthma
- 29 February 1984
- journal article
- research article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 14 (2) , 143-145
- https://doi.org/10.1111/j.1365-2222.1984.tb02645.x
Abstract
The effect of increasing concentrations of inhaled sodium cormoglycate (SG) (2, 10, 20 and 40 g/l) on histamine and methacholine bronchial reactivity was studied in 9 patients with extrinsic bronchial asthma. The responses to histamine and methacholine were expressed in terms of provocative concentrations producing 20% fall in the FEV1 [forced expiratory volume in 1 s] (PC20). The PC20 for histamine and methacholine was unaffected by all the concentrations of SCG used. Evidently, the effect of SCG on the bronchial smooth muscle or on the muscarinic receptors is minimal.This publication has 1 reference indexed in Scilit:
- Magnitude of Use and Costs of In-Hospital Respiratory Therapy1American Review of Respiratory Disease, 1980