Insulin and C-Peptide Levels in Obese Patients with Polycystic Ovaries

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Abstract
We studied two groups of obese patients, 16 affected by polycystic ovaries (OB-PCO) and 16 with simple obesity (OB), matched for age, relative weight and glucose values during oral glucose tolerance test. OB-PCO patients showed higher basal IRI levels and highere glucose stimulated IRI and CPR sezum levels. According to these results, hyperinsulism appears to be a common feature of PCO patients, relatively independent of the presence of obesity. Possible mechanisms are discussed.

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