Vessel wall and blood flow dynamics in arterial disease

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Abstract
Recent developments in ultrasound techniques have made it possible to investigate patients with arterial disease non-invasively by using Doppler blood velocity signal analysis. Since January 1979, 189 patients with pre-stroke syndromes have been investigated by using pulsed Doppler and real-time B-mode ultrasound imaging and waveform analysis. The results were that both imaging systems were highly (more than 92%) sensitive and specific when compared with conventional carotid arteriography. The ultrasound systems detected turbulence and could also be used to measure the distensibility of the arterial wall. The results show that varying grades of carotid stenosis can be demonstrated by two ultrasonic imaging systems, and that lateral scans are particularly helpful.