The Hypocholesterolizing Effects of Drugs
- 1 March 1956
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 4 (2) , 162-166
- https://doi.org/10.1161/01.res.4.2.162
Abstract
The hypocholesterolizing effect on serum and tissue cholesterol of α-phenylbutyramide (PB) is evident in the cholesterol-fed fowl. PB and Gallogen (the diethanolamine salt of the mono-(+)-camphoric acid ester of α,4-dimethylbenzyl alcohol) are mutually antagonistic with respect to this effect, while PB and soybean sterols are additive. The latter combination is approximately as effective as a Gallogen-soybean sterol combination, but has distinct toxic effects that are not observed with the Gallogen-soybean sterol combination.Keywords
This publication has 1 reference indexed in Scilit:
- Absorption of Cholesterol-4-C14 in Rats Fed Mixed Soybean Sterols and -Sitosterol.Experimental Biology and Medicine, 1953