A Comparison of Recombinant Hirudin with Heparin for the Treatment of Acute Coronary Syndromes
Open Access
- 12 September 1996
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 335 (11) , 775-782
- https://doi.org/10.1056/nejm199609123351103
Abstract
Thrombin has a pivotal role in the pathogenesis of acute coronary thrombosis. We compared the clinical efficacy of a potent, direct thrombin inhibitor, recombinant hirudin, with that of heparin (an indirect antithrombin agent) in patients with unstable angina or acute myocardial infarction.Keywords
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