Design and Synthesis of Potent, Non-peptide Inhibitors of HCV NS3 Protease
- 12 February 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (6) , 1157-1160
- https://doi.org/10.1016/s0960-894x(03)00032-5
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- A personal account of the role of peptide research in drug discovery: the case of hepatitis CJournal of Peptide Science, 2001
- Optimization of the P‘-Region of Peptide Inhibitors of Hepatitis C Virus NS3/4A ProteaseBiochemistry, 2000
- Hepatitis C Virus-Encoded Enzymatic Activities and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In VivoJournal of Virology, 2000
- Hepatitis C virus: an overview of current approaches and progressDrug Discovery Today, 1999
- The Scientific Challenge of Hepatitis CScience, 1999
- Hepatitis C virus NS3/4A proteaseAntiviral Research, 1998
- Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine proteaseBioorganic & Medicinal Chemistry Letters, 1998
- The conformation of hepatitis C virus NS3 proteinase with and without NS4A: a structural basis for the activation of the enzyme by its cofactorClinical and Diagnostic Virology, 1998
- Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwindingStructure, 1998
- The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding SiteCell, 1996