Cryosurgery in the treatment of lichen sclerosus et atrophicus of the vulva

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Abstract
Twelve patients with lichen sclerosus et atrophicus of the vulva were treated by a nitrous oxide cryoprobe. All had had severe itching which was relieved in the post‐operative period in 75% and for 3 years in 50%. Eight had histologically proven leukoplakia which cleared post‐operatively in five (62‐5%) and remained clear at three years in four (50%). In one patient pruritus, leukoplakia and ultimately squamous carcinoma appeared.

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