FAMILIAL EOSINOPHILIA
- 10 August 1940
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 115 (6) , 449-450
- https://doi.org/10.1001/jama.1940.72810320005009c
Abstract
The term familial eosinophilia implies the presence of an increase in mature eosinophilic leukocytes in the blood of several members of a family in whom none of the known causes of eosinophilia, such as allergic states, dermatoses and parasitic infestations, are found. In 1911 Klinkert called attention to this condition and reported a family of six with eosinophil counts ranging from 7 to 15 per cent; three of the children, however, exhibited allergic manifestations. In 1930 Armand-Delille, Hurst and Sorapure1reported a family in which a boy of 8 had an eosinophil count of between 51 and 62 per cent with a leukocyte count that at times reached 29,000. Three sisters and one brother had eosinophil counts of 14, 27, 27 and 21 per cent, while the father had one of 7 per cent. Two other children had normal blood counts. In 1933 Sloan Stewart2reported four familiesKeywords
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