The eosinophilic and amyloid‐like materials in adenomatoid odontogenic tumor

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Abstract
The relationship between eosinophilic material (EMt) and amyloid-like material in adenomatoid odontogenic tumors was evaluated. In duct-like structures and between opposing rows of tall columnar cells, EMt did not stain for amyloid. Under EM, EMt was composed of fibrillar and granular materials, and the fibrillar material was not amyloid. Two different kinds of EMt were found in solid cells masses. Lesions from cases 2, 3, 4 and part of case 1 contained small droplet-shaped EMt and these EMt did not stain for amyloid. Case 1 also contained EMt that stained positively for amyloid. The structure of amyloid positive EMt resembled developing enamel of human tooth germs. This material was tubular and finely granular. The tubular material resembled enamel matrix fibers rather than amyloid, and the fine granular material was stippled. The cells surrounding EMt appeared similar to ameloblasts between secretory and maturation stages.