Exposure to the parkinsonian neurotoxin 1-methyl-4-phenylpyridinium (MPP+) and nitric oxide simultaneously causes cyclosporin A-sensitive mitochondrial calcium efflux and depolarisation
- 1 February 1996
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 51 (3) , 267-273
- https://doi.org/10.1016/0006-2952(95)02165-5
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Advances in Our Understanding of the Mechanisms of the Neurotoxicity of MPTP and Related CompoundsJournal of Neurochemistry, 1993
- MPP+ and MPDP+ induced oxygen radical formation with mitochondrial enzymesFree Radical Biology & Medicine, 1993
- Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoraductase by rotenone, piericidin A, and MPP+Biochemical and Biophysical Research Communications, 1992
- Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicityJournal of Neuroscience, 1992
- Irreversible Inhibition of Mitochondrial Complex I by 1‐Methyl‐4‐Phenylpyridinium: Evidence for Free Radical InvolvementJournal of Neurochemistry, 1992
- MPTP mechanisms of neurotoxicity and their implications for Parkinson's diseaseEuropean Journal of Pharmacology: Molecular Pharmacology, 1991
- 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particlesBiochemical and Biophysical Research Communications, 1990
- Reaction of No With O2−. Implications for the Action of Endothelium-Derived Relaxing Factor (EDRF)Free Radical Research Communications, 1990
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitroBiochemical Pharmacology, 1988
- MPTPNeurology, 1986