Heterozygote advantage in cystic fibrosis: mosquito tests

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Abstract
Tests to demonstrate a preference by mosquitoes for stinging [human] controls as opposed to obligate heterozygotes for cystic fibrosis proved negative. If a heterozygote advantage caused a lower malarial incidence in carriers in South West Africa, it must have worked through the malarial parasite being adversely affected by a serum factor. This remains to be tested.