A Simple, Efficient Synthesis of N6-[bis(ethylamino) methylene]-N2-[(1,1-dimethylethoxy)carbonyl]-lysine (Boc-diethylhomoarginine)
- 1 December 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (22) , 3433-3437
- https://doi.org/10.1080/00397919008051585
Abstract
The synthesis of N6-(bis(ethylamino)methylene]-N2-[(1,1-dimethyl ethoxycarbonyl] lysine (Boc-diethylhomoarginine) by regiospecific amidination of lysine with (ethylamino) (ethylimino)-methanesulfonic acid (2) is described.Keywords
This publication has 9 references indexed in Scilit:
- The Synthesis of Aminoiminoethanenitriles, 5-Aminotetrazoles, N-Cyanoguanidines, and N-Hydroxyguanidines from Aminoiminomethanesulfonic AcidsSynthetic Communications, 1990
- Potent, long-acting luteinizing hormone releasing hormone antagonists containing new synthetic amino acids: N,N'-dialkyl-D-homoargininesJournal of Medicinal Chemistry, 1988
- A convenient synthesis of guanidines from thioureasThe Journal of Organic Chemistry, 1986
- A Facile Conversion of Amino Acids to Guanidino AcidsSynthesis, 1986
- Determination ofD-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzeneCarlsberg Research Communications, 1984
- Synthesis and biological activity of some very hydrophobic superagonist analogs of luteinizing hormone-releasing hormoneJournal of Medicinal Chemistry, 1982
- Amidines and related compounds. 6. Structure-activity relations of antihypertensive and antisecretory agents related to clonidineJournal of Medicinal Chemistry, 1975
- Peptide, XII. Synthese eines linearen Dekapeptids mit potentieller modifizierter Circulin‐SequenzJournal für Praktische Chemie, 1969
- 95. Zwei Synthesen des α-Melanotropins (α-MSH) mit Hilfe leicht entfernbarer Schutzgruppen)Helvetica Chimica Acta, 1963