Indoor survey of moulds and prevalence of mould atopy in Israel
- 1 February 1999
- journal article
- research article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 29 (2) , 186-192
- https://doi.org/10.1046/j.1365-2222.1999.00403.x
Abstract
Moulds are ubiquitous indoor as well as outdoor allergens and therefore potential candidates for indoor environmental control measures. However, very few studies have been performed to examine the significance of indoor moulds in allergic diseases and the effectiveness of measures to reduce the quantity of indoor moulds has not been established. To determine the significance and the contribution of moulds to allergic manifestations. Prevalence of allergic rhinitis and asthma in 395 members of a rural community were examined by questionnaire and examination of medical files. The atopic status in general and allergy to moulds was determined by skin-prick tests (SPTs) to a panel of aeroallergens including Aspergillus, Penicillium, Alternaria and Cladosporium. A study of indoor mould levels was performed by placing SDA plates in 59 houses. The type of fungi and the number of colonies from each species were recorded. Forty-two subjects, comprising 10.9% of the study group had positive SPT to moulds, 61.9% of those were classified as symptomatic. When taking into account individuals with a borderline positive SPT to moulds, an additional 23 had positive results. Of the 65 mould-positive subjects, 48% were symptomatic and of the 13 who were allergic to moulds alone, only two had allergic symptoms. Viable moulds were recovered from all 59 houses examined. The most common isolated genus was Aspergillus, followed by Penicillium, Alternaria and Cladosporium. Aspergillus was also the most abundant mould in houses. There was no significant correlation between the abundance of moulds, positive SPT to that mould and symptomatology. Viable moulds are common in houses in temperate climates. Allergy to moulds itself has a low predictive value to development of allergic symptoms, but allergy to moulds in otherwise atopic subjects increases the risk of symptomatic allergic disease.Keywords
This publication has 20 references indexed in Scilit:
- Influence of allergen avoidance on the eosinophil phase of airway inflammation in children with allergic asthmaPublished by Elsevier ,1996
- The importance of the pecan tree pollen in allergic manifestationsClinical and Experimental Allergy, 1996
- The control of allergens of dust mites and domestic pets: a position paperClinical and Experimental Allergy, 1992
- Presence of viable mould propagules in indoor air in relation to house damp and outdoor airAllergy, 1992
- Clinical and immunologic reactivity of patients allergic to grass pollens and to multiple pollen species: I. Clinical and immunologic characteristicsJournal of Allergy and Clinical Immunology, 1991
- Mould spores and yeasts in outdoor airAllergy, 1985
- REDUCTION OF BRONCHIAL HYPERREACTIVITY DURING PROLONGED ALLERGEN AVOIDANCEThe Lancet, 1982
- A Three‐Year‐Survey of Microfungi in the Air of Copenhagen 1977–79Allergy, 1981
- Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan: IV. Natural historyJournal of Allergy and Clinical Immunology, 1974
- Air-borne fungi in eilat and tel-hashomer, IsraelJournal of Allergy, 1962