Isolation and Hypoglycemie Activity of Anemarans A, B, C and D, Glycans ofAnemarrhena asphodeloidesRhizomes1

Abstract
An aqueous methanol/water extract of the Oriental crude drug “chimo”, Anemarrhena asphodeloides rhizomes, exhibited a marked hypoglycemie activity on dosing to mice. Fractionation of the extract, by monitoring the pharmacological activity, resulted in isolation of four glycans, anamerans A, B, C and D. These constituents displayed significant hypoglycemie effects in normal and alloxan-produced hyperglycemie mice.

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