Adh expression in species of themulleri subgroup ofDrosophila

Abstract
The locus encoding the NAD-dependent alcohol dehydrogenase (alcohol:NAD oxidoreductase; EC 1.1.1.1) is duplicated in some species of the cactophilicmulleri subgroup ofDrosophila. Here we report a survey on the expression throughout development and in different tissues for this system, its regulation using interspecific hybrids, and the effects induced by 2-propanol in 10 species belonging to four different clusters of the abovementioned subgroup. Our results indicate different expression throughout development and in different tissues,cis regulation in hybrid ovaries,trans (−) regulation in hybrid adults, and different responses to 2-propanol.