Application of self-assembly techniques in the design of biocompatible protein microarray surfaces
- 1 September 2002
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 23 (18) , 3097-3105
- https://doi.org/10.1002/1522-2683(200209)23:18<3097::aid-elps3097>3.0.co;2-g
Abstract
This review focuses on the application of novel technologies for generating biocompatible surfaces for high-throughput screening (HTS) of proteins. Various methods of coupling and spotting proteins on self-assembled monolayer (SAM) surfaces will be described along with the protein chip challenges pertaining to spot homogeneity, morphology, biocompatibility and reproducibility.Keywords
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