Assessment of genotoxic potential of pulp mill effluent and an effluent fraction using ames mutagenicity and Umu‐C genotoxicity assays

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Abstract
The Ames Mutagenicity Fluctuation and the Umu‐C genotoxicity bioassays were applied to assess the genotoxic potential in pulp mill effluents and their fractions. Mutagenicity was measured in the filtered effluents and the methanol extract of the diethyl‐amino‐ethyl cellulose. (DEAE) adsorbed materials by the Ames Fluctuation assay. The Umu‐C genotoxicity assay was applied only to the methanol extract of the DEAE adsorbed materials. Data indicate that the majority of the mutagenic substances from the filtered effluent were adsorbed by the DEAE cellulose and were effectively recovered with methanol. Approximately 1/3n to 1/6 of the materials in the effluent passed through the DEAE cellulose. The responses of the test organisms to genotoxic substances in the methanol extract fractions were comparable, suggesting that either one of these two bioassays could be used in screening pulp and paper effluents for genotoxicity. © by John Wiley & Sons, Inc.

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