Enantioselective Michael Reaction Catalyzed by Well-Defined Chiral Ru Amido Complexes: Isolation and Characterization of the Catalyst Intermediate, Ru Malonato Complex Having a Metal−Carbon Bond
- 29 May 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (25) , 7508-7509
- https://doi.org/10.1021/ja035435b
Abstract
Chiral Ru amido complexes promote asymmetric Michael addition of malonates to cyclic enones, leading to Michael adducts with excellent ee's, in which the chiral Ru amido complexes react with malonates to give isolable catalyst intermediates, chiral Ru malonato complexes bearing a metal bound C-nucleophile.Keywords
This publication has 7 references indexed in Scilit:
- A Five-Component Synthesis of Hexasubstituted BenzeneAngewandte Chemie International Edition in English, 2002
- Deprotonation of Organic Compounds Bearing Acid Protons Promoted by Metal Amido Complexes with Chiral Diamine Ligands Leading to New Organometallic CompoundsOrganometallics, 2002
- Metal−Ligand Bifunctional Catalysis: A Nonclassical Mechanism for Asymmetric Hydrogen Transfer between Alcohols and Carbonyl CompoundsThe Journal of Organic Chemistry, 2001
- Kinetic Resolution of Racemic Secondary Alcohols by RuII‐Catalyzed Hydrogen TransferAngewandte Chemie International Edition in English, 1997
- Asymmetric Transfer Hydrogenation Catalyzed by Chiral Ruthenium ComplexesAccounts of Chemical Research, 1997
- Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by Chiral Ruthenium(II) ComplexesJournal of the American Chemical Society, 1995
- Catalytic Asymmetric Michael Reactions Promoted by a Lithium-Free Lanthanum-BINOL ComplexJournal of the American Chemical Society, 1994