GENTAMICIN TISSUE CONCENTRATION IN VARIOUS AVIAN SPECIES FOLLOWING RECOMMENDED DOSAGE THERAPY

  • 1 January 1981
    • journal article
    • research article
    • Vol. 42  (12) , 2114-2116
Abstract
Plasma and tissue drug concentrations were compared in 6 eastern bobwhite quail (Colinus virginianus virginianus) and pigeons (Columba livia) given gentamicin by i.m. administration at the dosage of 10 mg/kg and in greater sandhill cranes (Grus canadensis tabida) and hybrid rosybill ducks (Netta sp.) given the same antibiotic at a dosage of 5 mg/kg. Quail and cranes had significantly higher liver concentrations of gentamicin at 6 h after injection than did pigeons and ducks. Cranes had significantly higher plasma concentrations than did ducks at 6 h after injection. Compared with plasma values, gentamicin concentrations were significantly higher in the liver of cranes at 12 h after injection and in the kidneys at 18 h.

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