PATTERN OF THE HUMAN CHORIONIC SOMATOMAMMOTROPHIC (HCS) CONCENTRATION RATIO IN MATERNAL SERUM AND AMNIOTIC FLUID DURING NORMAL PREGNANCY

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Abstract
Human chorionic somatomammotrophic (HCS) concentrations were measured in the maternal serum and amniotic fluid by means of radioimmunoassay. The HCS ratio of the concentration in the amniotic fluid and maternal serum decreases continuously from the 11th to the 40th week of gestation. This decrease is statistically highly significant. Several hypotheses are discussed to explain this decreasing ratio between the maternal compartment and the amniotic fluid.