Substitution of -Alanine, Nicotinic Acid, and Pimelic Acid for Meat Extract in Growth of Diphtheria Bacillus

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Abstract
Minute amounts of nicotinic acid, β-alanine, and pimelic acid, present together, permit about two-thirds the maximal growth of the diphtheria bacillus obtained from whole tissue extracts when added to a suitable control medium. The pimelic acid appears to be the least essential of the three. Differences appear between strains, even of the Park 8 organism, which may well be multiplied when further strains are examined.

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