Annulment of Sterol-Induced Sexual Reproduction by Estradiol in Pythium periplocum

Abstract
Estradiol prevented cholesterol-induced sexual reproduction by the fungus Pythium periplocum. Inhibition by estradiol was partial at 10- 6 M and complete at 10- 5 M , the same concentrations at which cholesterol and β-sitosterol were initially and maximally active. Higher concentrations of estradiol were required for growth inhibition than for inhibition of reproduction.