Effective detergent/lipid ratios in the solubilization of phosphatidylcholine vesicles by Triton X‐100
- 11 May 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 302 (2) , 138-140
- https://doi.org/10.1016/0014-5793(92)80424-f
Abstract
Effective detergent:lipid ratios (i.e. molar ratios in the mixed aggregates, vesicles or micelles) have been estimated for the solubilization of phosphatidylcholine vesicles by Triton X-100. Effective molar ratios are given for both the onset and the completion of bilayer solubilization; small unilamellar, large unilamellar and multilamellar vesicles have been used. Effective detergent:lipid ratios are independent of phospholipid concentration, and their use allows a deeper understanding of membrane-surfactant interactions.Keywords
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