Characterization of in Vitro T-Lymphocyte Colonies from Spleens of Nude Mice
Open Access
- 1 February 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 122 (2) , 582-584
- https://doi.org/10.4049/jimmunol.122.2.582
Abstract
Cells residing in the spleens of nude mice that appear Thy-1 negative can give rise to Thy-1 positive colonies in an in vitro culture system. Cells from pooled colonies can provide an accessory cell required for the development of cytotoxic lymphocytes from their precursors in an in vitro mixed lymphocyte reaction. As few as 50 such colony cells produce detectable activity.This publication has 0 references indexed in Scilit: