Immunotherapy of Superficial Dermatomycoses

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Abstract
The long-range efficacy of the standard treatment for superficial dermatomycoses is, in the majority of cases, unsatisfactory, even despite the advent of griseofulvin. The present paper reports an attempt to treat patients suffering from superficial dermatomycoses (Monilia and tinea) by specific immunotherapy. The follow-up period on patients receiving a full course of immunotherapy was 18 months. Of 39 patients receiving immunotherapy with Trichophyton as antigen, 22 were cured completely and an additional 4 showed partial cure (skin lesion healed but nails unaffected). Of 24 patients treated with Monilia antigen, 15 recovered completely. These results, although based on a limited number of cases, are fairly encouraging and point to immunotherapy as an additional method in the treatment of superficial dermatomycoses.

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