Alcohol abuse in chronic schizophrenics: implications for management in the community
- 1 September 1991
- journal article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 84 (3) , 272-276
- https://doi.org/10.1111/j.1600-0447.1991.tb03143.x
Abstract
This study was designed to investigate the effects of regular alcohol consumption on chronic schizophrenic patients maintained on fluphenazine decanoate in the community. A group of patients who consumed more than 20 units of alcohol per week was compared with those who did not drink or did so only occasionally. It was found that patients in the alcohol group had a higher frequency of previous relapses, a greater severity of positive symptoms and a lower incidence of extrapyramidal side effects except tardive dyskinesia for which there was no difference. Serum fluphenazine levels were lower in this group (NS). It was concluded that patients who regularly consume alcohol tend to be clinically unstable, perhaps because of poor therapeutic control.Keywords
This publication has 19 references indexed in Scilit:
- Plasma Levels of Fluphenazine DecanoateThe British Journal of Psychiatry, 1988
- Treatment of SchizophreniaSchizophrenia Bulletin, 1987
- Interactions between Procyclidine and Neuroleptic DrugsThe British Journal of Psychiatry, 1986
- Effects of smoking on fluphenazine clearance in psychiatric inpatientsBiological Psychiatry, 1985
- Adverse effects of anticholinergic medication on positive schizophrenic symptomsPsychological Medicine, 1983
- The discontinuance of maintenance neuroleptic therapy in chronic schizophrenic patients: drug and social consequencesActa Psychiatrica Scandinavica, 1983
- Plasma fluphenazine levels by radioimmunoassay in schizophrenic patients treated with depot injections of fluphenazine decanoate.Published by Wiley ,1979
- The effects of ethanol alone and in combination with phenobarbital, chlorpromazine, or chlordiazepoxideToxicology and Applied Pharmacology, 1969
- Do Psychiatric In-Patients Take their Pills?The British Journal of Psychiatry, 1967
- A FOLLOW‐UP OF SCHIZOPHRENIC PATIENTS IN EDINBURGHActa Psychiatrica Scandinavica, 1963