EFFECT OF ACTINOMYCIN-D ON PROTEIN, RIBONUCLEIC ACID, AND ENZYME FORMATION IN BACILLUS SUBTILIS

Abstract
Effects of actinomycin-D on protein synthesis, RNA synthesis, and on formations of amylase, protease, alkaline phosphatase, and ribonuclease in Bacillus subtilis K were investigated. The RNA synthesis and the protein synthesis were inhibited quite similarly by actinomycin-D of various concentrations. Inhibition of the formation of amylase, protease, and alkaline phosphatase was also similar, but ribonuclease formation was quite resistant and was stimulated markedly at a lower concentration of actinomycin-D.

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