Dihydrotubastrines: Phenethylguanidine Analogues from the Indo-Pacific Marine Sponge Petrosia cf. contignata
- 22 May 1998
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 61 (6) , 859-861
- https://doi.org/10.1021/np980061z
Abstract
Two phenethylguanidine derivatives, 7,8-dihydrotubastrine (1) and 4-deoxy-7,8-dihydrotubastrine (2), along with the sterol xestobergsterol A (3), were isolated from the marine sponge Petrosia cf. contignata. The structures of the new natural products 1 and 2 were based on spectroscopic data and comparison to the literature properties for semisynthetic 1. This is the first example from this compound class with a saturated acyclic C2 unit.Keywords
This publication has 14 references indexed in Scilit:
- Haliclostanone Sulfate and Halistanol Sulfate from an Indo-Pacific Haliclona SpongeJournal of Natural Products, 1997
- The structure and biogenetic origin of (-) halicyclamine B from a Xestospongia spongeTetrahedron Letters, 1996
- Taccalonolides from tacca plantagineaPhytochemistry, 1996
- Narains: N, N-dimethylguanidinium styryl sulfates, metamorphosis inducers of ascidian larvae from a marine sponge Jaspis spTetrahedron Letters, 1994
- Isojaspisin: A novel styryl sulfate from a marine sponge, Jaspis sp., that inhibits hatching of sea urchin embryosTetrahedron Letters, 1994
- An alkaloid protein kinase C inhibitor, xestocyclamine A, from the marine sponge Xestospongia spJournal of the American Chemical Society, 1993
- Two unique pentacyclic steroids with cis C/D ring junction from Xestospongia bergquistia Fromont, powerful inhibitors of histamine releaseThe Journal of Organic Chemistry, 1992
- A blind comparison of simple bench‐top bioassays and human tumour cell cytotoxicities as antitumor prescreensPhytochemical Analysis, 1991
- Novel Marine Sponge Amino Acids, 10. Xestoaminoh from Xestaspongia sp.Journal of Natural Products, 1990
- Antimicrobial metabolites of the marine spongeAxinella polycapellaCellular and Molecular Life Sciences, 1981