ON THE LYSIN PRESENT IN NORMAL URINE
- 28 February 1934
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 107 (3) , 603-609
- https://doi.org/10.1152/ajplegacy.1934.107.3.603
Abstract
This paper reports an attempt to identify the lysin present in normal human and animal urine. The lysin is remarkably heat stable, is soluble in ethyl alcohol but not in most organic solvents, is diffusible, adsorbed on activated charcoal, inhibited by plasma proteins, lecithin, and cholesterol, and is irreversibly destroyed at pH 8-9. It is not the bile acids or their salts, and its activity is much more highly correlated with the pH of the urine than with its surface tension. It may be one of the un identified components of the urine, but its properties are very like those of certain bacterial hemolysins, and in particular like those of the lysin of B. coli.This publication has 1 reference indexed in Scilit:
- A study of certain forms of inhibition and acceleration of hæmolysisProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1926