A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion

This publication has 19 references indexed in Scilit:

• Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
  Published by Elsevier ,2004
• Oxidation of N‐Methyl‐1,2,3,4‐Tetrahydroisoquinoline into the N‐Methyl‐Isoquinolinium Ion by Monoamine Oxidase
  Journal of Neurochemistry, 1989
• Migration of tetrahydroisoquinoline, a possible parkinsonian neurotoxin, into monkey brain from blood as proved by gas chromatography—mass spectrometry
  Journal of Chromatography A, 1988
• Effect of long-term administration of 1,2,3,4-tetrahydroisoquinoline (TIQ) on striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) content in mice
  Neuroscience Letters, 1988
• An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions
  Neuroscience Letters, 1988
• Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroquinoline in Parkinsonian and normal human brains
  Biochemical and Biophysical Research Communications, 1987
• Inhibition of Monoamine Oxidase by N-Methylisoquinolinium Ion
  Journal of Neurochemistry, 1987
• The effects of pyridinium salts, structurally related compounds of 1-methyl-4-phenylpyridinium ion (MPP+), on tyrosine hydroxylation in rat striatal tissue slices
  Brain Research, 1986
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976
• Ueber tertiäre und quaternäre Tetrahydroisochinolinbasen; ein Beitrag zur Stereochemie des Stickstoffs
  European Journal of Inorganic Chemistry, 1901