The Mitochondrion

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Abstract
Oxidative PhosphorylationAt certain points along the respiratory chain some of the energy produced by oxidation-reduction is used to form the high-energy phosphate bond of ATP. The process that couples the esterification of inorganic phosphate (ADP + Pi = ATP) to electron transport is known as "oxidative phosphorylation."Belitzer and Tzibakova,58 in 1939, and Ochoa,59 two years later, demonstrated a stoichiometry between oxygen consumption (or electron transport) and inorganic phosphate esterification. It was subsequently shown that for each pair of reducing equivalents transferred from an NAD-linked substrate to oxygen, 3 inorganic phosphate anions were esterified, giving a ratio of inorganic . . .