THE EFFECTS OF IONS ON THE BINDING OF AGONISTS AND ANTAGONISTS TO MUSCARINIC RECEPTORS
Open Access
- 1 November 1979
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 67 (3) , 371-377
- https://doi.org/10.1111/j.1476-5381.1979.tb08690.x
Abstract
1 There are no selective effects of Na+, K+, Ca2+, Mg2+ or Cl− on the binding of antagonists or agonists to muscarinic receptors in rat brain. A decrease in affinity related to ionic strength is found for all these ions. 2 Larger effects were produced by T+, La3+, and some transition metal ions.Keywords
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