MICROMETHOD FOR STIMULATION OF CHICKEN LYMPHOCYTES INVITRO USING WHOLE-BLOOD

  • 1 January 1976
    • journal article
    • research article
    • Vol. 26  (3) , 641-646
Abstract
A simple, rapid and reproducible micromethod for determination of in vitro mitogenic [phytohemagglutinin and concanavalin A] responses of chicken peripheral blood lymphocytes is described. The test utilizes 5 .mu.l volumes of heparinized whole blood, 125I-labeled 5-iodo-2''-deoxyuridine with 5-fluoro-2''-deoxyuridine in place of [3H]thymidine and a multiple cell-culture harvester. The method permits a close follow-up of the mitogenic responses in the chicken.