Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus
Open Access
- 6 May 2008
- journal article
- Published by Springer Nature in British Journal of Cancer
- Vol. 98 (11) , 1797-1802
- https://doi.org/10.1038/sj.bjc.6604376
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Pharmacokinetic Profile of Temsirolimus With Concomitant Administration of Cytochrome P450‐Inducing Medications1The Journal of Clinical Pharmacology, 2007
- Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell CarcinomaNew England Journal of Medicine, 2007
- Everolimus drug interactions: application of a classification system for clinical decision makingBiopharmaceutics & Drug Disposition, 2006
- Randomized Phase II Study of Multiple Dose Levels of CCI-779, a Novel Mammalian Target of Rapamycin Kinase Inhibitor, in Patients With Advanced Refractory Renal Cell CarcinomaJournal of Clinical Oncology, 2004
- Determination of Volume of Distribution at Steady State with Complete Consideration of the Kinetics of Protein and Tissue Binding in Linear PharmacokineticsJournal of Pharmaceutical Sciences, 2004
- mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4EMolecular and Cellular Biology, 2004
- Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumorsAnnals of Oncology, 2003
- Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of RapamycinMolecular and Cellular Biology, 2002
- TOR, a Central Controller of Cell GrowthCell, 2000
- Pharmacokinetic-Pharmacodynamic Consequences and Clinical Relevance of Cytochrome P450 3A4 InhibitionClinical Pharmacokinetics, 2000