Do metastases metastasize?
- 13 April 2004
- journal article
- review article
- Published by Wiley in The Journal of Pathology
- Vol. 203 (1) , 515-518
- https://doi.org/10.1002/path.1544
Abstract
Metastatic disease is a major cause of morbidity and mortality. However, it is not clear if all metastases originate from the primary tumour or whether metastases themselves have the capacity to metastasize. In this review, the evidence for the latter phenomenon, and its biological and clinical implications, is discussed.Keywords
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