Efficacy of paracetamol in reducing post‐operative pain after periodontal surgery

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Abstract
In a double‐blind, placebo‐controlled study, the efficacy of 2 doses of paracetamol (500 and 1000 mg) was assessed in post‐operative pain after periodontal flap surgery. Both doses of paracetamol provided greater analgesia than placebo, however, significant analgesia (P < 0.05) was only noted in the early post‐operative period. The analgesia from both doses of paracetamol did not differ significantly throughout the 3‐day observation period, however, greater analgesia was attributable to 1000 mg paracetamol in the immediate post‐operative period. The results from this study suggest that paracetamol is an effective analgesic for controlling posi‐operative pain after periodontal flap surgery, with 1000 mg dose being more effective than 500 mg immediately after surgery.